| 1. | | Psilocybin for major depression granted Breakthrough Therapy by FDA (newatlas.com) |
| 1240 points by elorant on Nov 26, 2019 | 466 comments |
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| 2. | | The Real Class War (americanaffairsjournal.org) |
| 773 points by arcanus on Nov 26, 2019 | 608 comments |
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| 3. | | Machine Learning on Encrypted Data Without Decrypting It (juliacomputing.com) |
| 421 points by KenoFischer on Nov 26, 2019 | 116 comments |
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| 4. | | RISC-V Foundation moving to Switzerland over trade curb fears (reuters.com) |
| 379 points by thesausageking on Nov 26, 2019 | 269 comments |
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| 5. | | Reverse Engineering for Beginners [pdf] (beginners.re) |
| 451 points by dennis714 on Nov 26, 2019 | 49 comments |
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| 6. | | Show HN: Coscreen.co – a radically different remote collaboration tool (coscreen.co) |
| 404 points by coscreen on Nov 26, 2019 | 184 comments |
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| 7. | | Eternal Terminal (eternalterminal.dev) |
| 373 points by ofrzeta on Nov 26, 2019 | 101 comments |
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| 8. | | Toshiba device tests cancer types from a drop of blood (japantimes.co.jp) |
| 197 points by hospes on Nov 25, 2019 | 91 comments |
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| 9. | | Our Startup Handbook (versionone.vc) |
| 278 points by yarapavan on Nov 26, 2019 | 20 comments |
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| 10. | | Show HN: patchbay.pub – Poor man's ngrok/IFTTT/serverless (patchbay.pub) |
| 362 points by apitman on Nov 26, 2019 | 79 comments |
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| 11. | | Latency/throughput tradeoffs, illustrated with coffee (medium.com/kentbeck_7670) |
| 160 points by KentBeck on Nov 26, 2019 | 32 comments |
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| 12. | | BorgBackup: Deduplicating Archiver (borgbackup.org) |
| 258 points by colinprince on Nov 26, 2019 | 103 comments |
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| 13. | | Health Concerns Mount as More Old Sewer Pipes Are Lined with Plastic (scientificamerican.com) |
| 200 points by Bender on Nov 26, 2019 | 66 comments |
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| 14. | | The LEGO Group acquires BrickLink (brickset.com) |
| 261 points by ivanech on Nov 26, 2019 | 137 comments |
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| 15. | | Big Calculator: How Texas Instruments Monopolized Math Class (gen.medium.com) |
| 211 points by lewisflude on Nov 26, 2019 | 229 comments |
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| 16. | | GitHub satanically messing with Markdown – changes 666 to DCLXVI (stackoverflow.com) |
| 229 points by YeGoblynQueenne on Nov 24, 2019 | 91 comments |
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| 17. | | Jennicam: The first woman to stream her life on the internet (2016) (bbc.com) |
| 135 points by wallflower on Nov 24, 2019 | 70 comments |
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| 18. | | Pirate Act: what the law says and how it threatens pirate radio stations (theverge.com) |
| 84 points by Tomte on Nov 26, 2019 | 80 comments |
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| 19. | | FortiGuard XOR Encryption in Multiple Fortinet Products (seclists.org) |
| 146 points by andromaton on Nov 26, 2019 | 89 comments |
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| 20. | | JSONCrush – Compress JSON into URI Friendly Strings (github.com/killedbyapixel) |
| 121 points by KilledByAPixel on Nov 26, 2019 | 62 comments |
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| 21. | | How machine learning is revolutionising market intelligence (economist.com) |
| 81 points by known on Nov 25, 2019 | 19 comments |
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| 22. | | Launch HN: Scanwell (YC S18) – At-home UTI test with same-day treatment options |
| 87 points by stephenlchen on Nov 26, 2019 | 33 comments |
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| 23. | | Stop Teaching Code, Solicit Predictions Instead (upperlinecode.com) |
| 230 points by wallflower on Nov 24, 2019 | 56 comments |
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| 24. | | The Birth of Legacy Software – How Change Aversion Feeds on Itself (rajivprab.com) |
| 113 points by whack on Nov 25, 2019 | 66 comments |
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| 25. | | Instagram’s Explore Recommender System (instagram-engineering.com) |
| 109 points by YoavShapira on Nov 26, 2019 | 55 comments |
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| 26. | | The Worst Businessman of the 18th Century BC (2018) (forbes.com/sites/kristinakillgrove) |
| 80 points by respinal on Nov 25, 2019 | 39 comments |
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| 27. | | Google Fires Four Workers, Including Staffer Tied to Protest (bloomberg.com) |
| 397 points by phissk on Nov 26, 2019 | 353 comments |
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| 28. | | Emacs: The Editor for the Next Forty Years [video] (emacsconf.org) |
| 251 points by rgrau on Nov 26, 2019 | 269 comments |
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| 29. | | Vinod Khosla Wins Ruling Threatening Public Beach Access (bloomberg.com) |
| 307 points by chollida1 on Nov 26, 2019 | 333 comments |
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| 30. | | Lightweight API Design in Swift (swiftbysundell.com) |
| 109 points by ingve on Nov 25, 2019 | 56 comments |
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