| 1. | | A farewell to bioinformatics (2012) (madhadron.com) |
| 337 points by emcl on Jan 27, 2013 | 170 comments |
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| 2. | | We don't know why lithium batteries work (shkrobius.livejournal.com) |
| 269 points by mike_esspe on Jan 27, 2013 | 105 comments |
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| 3. | | Github SSL replaced by self-signed certificate in China |
| 189 points by teawithcarl on Jan 27, 2013 | 75 comments |
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| 4. | | Python Shortcuts for the Python Beginner (maxburstein.com) |
| 187 points by mburst on Jan 27, 2013 | 53 comments |
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| 5. | | Why do game developers prefer Windows? (programmers.stackexchange.com) |
| 177 points by siamore on Jan 27, 2013 | 129 comments |
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| 6. | | Building Firefox OS (buildingfirefoxos.com) |
| 168 points by bpierre on Jan 27, 2013 | 71 comments |
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| 7. | | There's More to Life Than Being Happy (theatlantic.com) |
| 160 points by dmor on Jan 27, 2013 | 48 comments |
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| 8. | | Machine Learning Cheat Sheet (for scikit-learn) (peekaboo-vision.blogspot.de) |
| 158 points by stadeschuldt on Jan 27, 2013 | 8 comments |
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| 9. | | The 50 million dollar lie (teachforus.org) |
| 149 points by ColinWright on Jan 27, 2013 | 152 comments |
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| 10. | | "I Will Ruin Him" – How it feels to be stalked (chronicle.com) |
| 147 points by azakai on Jan 27, 2013 | 112 comments |
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| 11. | | It is ridiculously easy to refactor Go (onebigfluke.com) |
| 149 points by bslatkin on Jan 27, 2013 | 88 comments |
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| 12. | | PIN number analysis (datagenetics.com) |
| 134 points by Anon84 on Jan 27, 2013 | 82 comments |
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| 13. | | A few thoughts about Open Source Software (antirez.com) |
| 131 points by justincormack on Jan 27, 2013 | 136 comments |
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| 14. | | Systemd: The Biggest Myths (0pointer.de) |
| 131 points by janerik on Jan 27, 2013 | 114 comments |
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| 15. | | MindMup is now open source (mindmup.com) |
| 130 points by samuraijs on Jan 27, 2013 | 29 comments |
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| 16. | | The Python yield keyword explained (stackoverflow.com) |
| 127 points by interro on Jan 27, 2013 | 49 comments |
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| 17. | | Hubble - a terminal dashboard (github.com/jaymedavis) |
| 124 points by jaymedavis on Jan 27, 2013 | 10 comments |
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| 18. | | Hugh Laurie: Wodehouse Saved my Life (1999) (pgwodehousebooks.com) |
| 124 points by pclark on Jan 27, 2013 | 56 comments |
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| 19. | | We're hiring - but we probably won't pay you. (channelsource.org) |
| 116 points by celticbadboy on Jan 27, 2013 | 52 comments |
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| 20. | | IDIV DoS (INT_MIN / -1) (kqueue.org) |
| 111 points by alter8 on Jan 27, 2013 | 23 comments |
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| 21. | | In Love with LÖVE (ton.io) |
| 110 points by replicatorblog on Jan 27, 2013 | 72 comments |
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| 22. | | Inside the ALU of the 8085 microprocessor (arcfn.com) |
| 101 points by mariuz on Jan 27, 2013 | 17 comments |
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| 23. | | The Story Behind Banksy (smithsonianmag.com) |
| 99 points by rsobers on Jan 27, 2013 | 25 comments |
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| 24. | | Javascript Cryptography Considered Harmful (matasano.com) |
| 95 points by LVB on Jan 27, 2013 | 103 comments |
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| 25. | | Bpython is a fancy interface to Python (bpython-interpreter.org) |
| 88 points by interro on Jan 27, 2013 | 40 comments |
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| 26. | | Language Learning is Broken (thangudu.com) |
| 82 points by kumarski on Jan 27, 2013 | 56 comments |
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| 27. | | LibreOffice 4.0: The big changes will be under the hood (zdnet.com) |
| 82 points by CrankyBear on Jan 27, 2013 | 47 comments |
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| 28. | | New MySpace done with Node + Express (expressjs.com) |
| 82 points by tferris on Jan 27, 2013 | 46 comments |
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| 29. | | Show HN: My Weekend Project: One-Click Developer Portfolio Website (prtflio.eu) |
| 78 points by tjosten on Jan 27, 2013 | 52 comments |
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| 30. | | Islam and science: The road to renewal (economist.com) |
| 71 points by rosser on Jan 27, 2013 | 97 comments |
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| More |