They are similar as both built in C/C++ with performance in mind.
They are very different as Aerospike is a Key Value store, while Scylla, like Cassandra is Columnar (Key, Key, Value). This gives Scylla a much richer semantic.
There are more differences, like Aerospike holding all keys in memory, while Scylla does not have such limitation. I'm sure there are more differences in tunable consistency, HA and multi DC, but I'm not an Aerospike expert.