Yan-Chao Li [etal.] ABSTRACT
Swine hemagglutinating encephalomyelitis virus (HEV)
has been shown to have a capability to propagate via
neural circuits to the central nervous system after pe-
ripheral inoculation, resulting in acute deadly encepha-
lomyelitis in natural host piglets as well as in
experimental younger rodents. This study has system-
atically examined the assembly and dissemination of
HEV 67N in the primary motor cortex of infected rats
and provides additional evidence indicating that mem-
branous-coating-mediated endo-/exocytosis can be
used by HEV for its transsynaptic transfer. In addition,
our results suggested that this transsynaptic pathway
could adapted for larger granular materials, such as
viruses. These findings should help in understanding
the mechanisms underlying coronavirus infections as
well as the intercellular exchanges occurring at the syn-
aptic junctions. J. Comp. Neurol. 521:203–212, 2013.
that doesnt seem to be the case. this virus really likes your lungs because of a specific protien. this protien exists in your lungs at a greater concentration than elsewhere in your body. The virus would have to undergo a specific series of mutations to get good at targeting neurons.
yes, but there isn't a direct route from the outside to your brain. Your eye socket is relatively well insulated from the outside by skin, connective tissue, conjunctiva.
what you should take home from this is that you are not in immedate danger from a neurotrophic virus at this time.
what you should also take from this espescially if you are involved in policy is that this corona virus we are experiencing has in its distant heritage ancestors with reported neurotrophic properties. It is possible, that at some time in the future, this virus will accumulate signifigant genetic drift and gain or lose certain properties.
however:
Yan-Chao Li [etal.] ABSTRACT Swine hemagglutinating encephalomyelitis virus (HEV) has been shown to have a capability to propagate via neural circuits to the central nervous system after pe- ripheral inoculation, resulting in acute deadly encepha- lomyelitis in natural host piglets as well as in experimental younger rodents. This study has system- atically examined the assembly and dissemination of HEV 67N in the primary motor cortex of infected rats and provides additional evidence indicating that mem- branous-coating-mediated endo-/exocytosis can be used by HEV for its transsynaptic transfer. In addition, our results suggested that this transsynaptic pathway could adapted for larger granular materials, such as viruses. These findings should help in understanding the mechanisms underlying coronavirus infections as well as the intercellular exchanges occurring at the syn- aptic junctions. J. Comp. Neurol. 521:203–212, 2013.
https://doi.org/10.1002/cne.23171
it seems if you are not a swine or a rat you have little to worry about.