Yep! In fact I've tried interoperating with Datasette (e.g. shared here https://news.ycombinator.com/item?id=25090643 )

One secret sauce is using 'automatic' caching of data in sqlite -- this allows both for faster access and having an additional interface for the data as a collateral https://github.com/karlicoss/cachew#readme

Still need to polish this a bit, but ultimately hoping to properly plug into Datasette, I'm impressed by its data exploration capabilities!