One thing that it seems we are just starting to talk about with these drugs is the associated muscle and bone density loss. I'm concerned that this generation of GLP-1 early adopters will wind up more frail and suffer a lower quality of life in old age as a result.
Yes, but you would certainly still see some - it's just a consequence of weight loss. Even IFBB bodybuilders on god knows how many steroids see some muscle loss when cutting.
Eat a whole lot of protein, lift, and you're going to be doing more than fine in the muscle loss department.
My program strongly recommends some form of muscle training (pushups/weights/etc) as they see improvements from muscle development for weight loss and to counteract the muscle loss from losing weight.
The fact remains that having to carry around 50+ extra pounds of fat requires more muscle. When that requirement goes away so does your need for that musculature.
I've seen zero evidence that muscle loss from GLP-1-assisted weight-loss is any different to the muscle loss from simply eating less. Do you have a link to a study I've missed?
