I don't think that's what DOGE is doing. Seems extremely vindictive and ideological in the way it's acting and time will tell but I would not be surprised if it ends costing the taxpayers more in the long run.
Argentina and US are very different countries, starting these cuts with very different economic realities. For example, 55% of all registered workers are employed by the government in Argentina. Although not a directly comparable metric (since in the US you also need to account for state and local civil workers), the US federal government employs around 3 million people. That's just 1.87% of the entire civilian workforce.
Again, DOGE operates from the premise that the federal government is bloated. Although this is a very popular message, I'd love to see some more objective data to support this and I doubt that CDC or USAID are the agencies where the bloat is. Like I said, their actions seem vindictive and careless. Also, likely to result in legal cases that will drag for years and end up costing taxpayer more than the supposed savings.
The main con is that once you fire the workers that you thought you didn't need (but that you did indeed need) hiring them back becomes more expensive and a lengthy process. Some of the firings are already causing chaos in vital teams among several agencies and have forced DOGE to try to reverse course (bird flu monitoring, nuclear response...).
And that's not to mention the dire situation you put the people you are firing in. Laying off people from their jobs is never "an experiment" unless you are willing to suspend every trace of empathy.