Mumble is awesome but definitely difficult to properly configure. Especially the TLS certs for any reverse proxy won't work directly, there's a hacky way to make it work which I don't fully trust
I work on a project in this space, and the endless insistence of people that they have to run clearly non-web things through reverse proxies always amazes me :)
Not everything is a web app, and it's trivial these days to obtain certificates, even without a proxy (certbot, etc.).
Of course I understand that if you host a lot of web apps, having all web requests routed through a universal proxy is nice for various reasons. But platforms like Discord and such are complex beasts and use more technologies than HTTP(S).