EGFR, as mentioned - it’s the most common cause of lung cancer in East Asian women.
TP53, as also mentioned - gives you a >90% chance of cancer of any variety in a lifetime. 50% by age 30.
Smoking presents about a 20% lifetime risk - and that’s without adjusting for genetic predispositions like CHRNA3/5 which increase nicotine addictiveness and promote tumorigenisis, or BRCA2, or CHEK2, which diminish DNA repair capabilities.
Quite strong claims. I would be interested to read more about those. Do you have any references you can point out? A quick research on EGFR and TP53 suggested they are more related to colorectal cancer and not the lung cancer.
TP53, as also mentioned - gives you a >90% chance of cancer of any variety in a lifetime. 50% by age 30.
Smoking presents about a 20% lifetime risk - and that’s without adjusting for genetic predispositions like CHRNA3/5 which increase nicotine addictiveness and promote tumorigenisis, or BRCA2, or CHEK2, which diminish DNA repair capabilities.